Some vitamins have documented side effects that are typically more extreme with a larger dosage. The water-soluble vitamins are vitamin C (ascorbic acid) and the B vitamins , which embrace thiamin (vitamin B1), riboflavin (vitamin B2), vitamin B6 , niacin (nicotinic acid), vitamin B12 , folic acid , pantothenic acid , and biotin These relatively easy molecules comprise the elements carbon, hydrogen, and oxygen; some also include nitrogen, sulfur , or cobalt.
Taking vitamin C along with vitamin E, beta-carotene, and selenium may decrease some of the useful results of niacin. Generally, individuals put vitamin C on their skin to protect it against the sun, pollutants, and different environmental hazards. Large quantities of vitamin C might decrease how much fluphenazine (Prolixin) is within the physique.
Vitamins A, D, and Okay are saved mainly within the liver, with smaller quantities stored in other comfortable body tissues; nonetheless, many of the stored vitamin E is found in body fat, although large amounts additionally occur within the uterus of females and testis of males.
An increased danger of sepsis occurred in a scientific trial (14% vs 6%) in which vitamin E was administered to untimely neonates with a birthweight of less than 1500 g. When high-dose vitamin E of as much as 30 mg/kg/day was administered to this inhabitants to prevent retrolental fibroplasia, necrotizing enterocolitis occurred.
Vitamin E is found in many foods, corresponding to vegetable oils, nuts, and inexperienced leafy vegetables. Vitamin B12 is found naturally in fish, pink meat, poultry, milk, cheese, and eggs. Taking vitamin C earlier than and after an angiography appears to scale back the danger of growing kidney problems. Vitamin Ok-1 dietary supplements are normally 2.5-10 mg. Phytonadione promotes liver synthesis of factors II, VII, IX, and X. The varied forms of vitamin E are stored in tissues in numerous amounts; alpha-tocopherol is saved in larger concentrations than are the other varieties. Taking vitamin C along with beta-carotene plus vitamin E does not cut back the risk of creating esophageal cancer. Vitamin E is present in vegetable oil, nuts, sunflower, wheat, green leafy greens, and fish.